Teacher
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PROIETTI Silvia
(syllabus)
First part of the program (4 CFU) General aspects of Biochemistry Weak interactions in aqueous systems. Chemical-physical properties of water. Ionization of water, weak acids and basics. Buffers.
Composition and structure of proteins Amino acids e their general properties. Peptide bond. Levels of organization of proteins: primary, secondary, tertiary and quaternary structures. Functional aspects of proteins. Myoglobin and haemoglobin.
Enzymes Fundamental concepts of enzymatic activity. Enzyme nomenclature, specificity, coenzymes and cofactors. Activation energy end role of enzymes. Overview of enzymatic kinetics.
Lipids, biological membranes and membrane proteins Fatty acids. Triacylglycerols. Glycerophospholipids. Lipidic and proteic components of biological membranes. Composition and architecture of biological membranes. Membrane proteins.
Carbohydrates Structure and function of carbohydrates. Oligosaccharides. Polysaccharides.
(reference books)
Nelson DL, Cox MM. Introduzione alla Biochimica di Lenhninger. 5a Edizione (2015) Zanichelli, Bologna. Voet D, Voet JG, Pratt CW. Fondamenti di Biochimica 3a Edizione (2013) Zanichelli, Bologna. Nelson DL, Cox MM. I principi di Biochimica di Lenhninger. 6a Edizione (2014) Zanichelli, Bologna. Berg JM, Tymoczko JL, Stryer L. Biochimica 7a Edizione (2012) Zanichelli, Bologna.
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