Teacher
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BUONOCORE Francesco
(syllabus)
Proteins used in the industrial sector with particular emphasis for the pharmaceutical scope. Production, purification and characterization of proteins used in biotechnology in different heterologous systems like bacteria, yeast, cell cultures, transgenic animals. Antibodies in diagnosis and as new drugs. Antimicrobial peptides with potential applications as antibiotics and antitumorals. The Phage Display approach to isolate new targets for drugs. Specific techniques used for the ingegnerization of proteins. Discussion of scientific papers related to specific themes of the course.
(reference books)
Main books: Watson J.D., Gilman M., Witkowski J., Zoller M. Recombinant DNA. 1992 Daan J. A. Crommelin, Robert D. Sindelar, Bernd Meibohm. Pharmaceutical Biotechnology: Fundamentals and Applications. Springer 2007
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