Teacher
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CEOLONI Carla
(syllabus)
- Introduction to Genetics. - The genetic material: chemical composition and structure of nucleic acids. Chromatin and chromosomes; structure of eukaryotic chromosome. - DNA replication. - From DNA to proteins: transcription; genetic code; translation and protein synthesis. - Control of gene expression in prokaryotes and eukaryotes. - Brief outline of genomics: size, types of sequences and organization of eukaryotic genomes (examples of sequenced animal and plant genomes, as compared to prokaryotic genomes). Chromosomes and chromatin; structure of the eukaryotic chromosome, karyotypes; chromatin organization: nucleosomes and super-coiling and effect on transcription; eu- and heterochromatin, banding. - Cell cycle, mitosis and meiosis. - Genetics and inheritance of simple traits: Mendel's laws - dominance and recessiveness, segregation in monohybrids and dihybrids, independent assortment, testcross, incomplete dominance, multiple alleles and codominance. Chromosome theory of inheritance. - Linkage and recombination; genetic maps. - Mutations: point mutations; chromosome rearrangements, transposable elements, genomic variations: polyploidy, aploidy, aneuploidy. - Brief outline of genetics of quantitative traits: continuous variation, mean and variance. Experiments by Nilsson-Ehle and Emerson-East. Heritability estimates, response to selection.
(reference books)
- Main textbook: Russell PJ .: Genetics - A molecular approach, Pearson publisher (or similar textbooks, preferably by the same author) - Teaching material of all the topics covered, including any insights, provided by the teacher and available on the teaching materials website
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