Teacher
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BIZZARRI Bruno Mattia
(syllabus)
Module A STRUCTURE Alkanes and cycloalkanes. Introduction. Structure. Sp3 hybridization. Nomenclature. Physical Properties. Isomerism of structure. Conformational analysis (ethane, cyclohexane). Stability of cycloalkanes (angle strain, torsional strain, tension steric). Derivatives of cyclohexane (stereoisomery cis-trans). Bicyclic alkanes and polycyclic. Natural role and applications of alkanes.
Alkenes. Introduction .. Structure. Sp2 hybridization. Nomenclature. Physical Properties. Stability (heat of hydrogenation, heat of combustion). Nomenclature system (E) - (Z) for alkenes. Cicloalcheni.Funzione biological.
Alkynes. Introduction. Structure. Sp hybridization. Nomenclature. Physical Properties.
Functional groups and classes of organic compounds. Alkyl halides. Alcohols. Ethers. Amines. Aldehydes and ketones. Carboxylic acids. Esters and amides. Introduction. Structure. Nomenclature. Physical Properties.
Stereochemistry. Introduction. Chirality of carbon. Enantiomers and chiral molecules. Graphical representation. Nomenclature (R) (S). Optical activity (specific optical rotation, definition of racemate, optical purity). Diastereoisomers (meso compounds). Chiral molecules without chiral carbons.
Aromatic compounds. Introduction. Benzene. Structure and stability. Huckel rule. Other aromatic compounds. Nomenclature of benzene derivatives. Induction phenomena and resonance. Heterocyclic aromatic compounds. The aromatic compounds in biochemistry.
Carbohydrates. Classification. Monosaccharides. Mutarotation and formation of glucosides. Configuration D or L. Disaccharides. Polysaccharides.
Protein. Structure of the amino acids. Nomenclature. Peptide bond. Oligopeptides.
Nucleic acids. Purine and pyrimidine nucleic bases. Nucleosides. Nucleotides. Oligonucleotides.
Lipids.
Form B. THE REACTIVITY '
Reactions of alkanes and cycloalkanes. Chlorination of methane. Free radicals. Stability and structure. Thermodynamics and kinetics. Halogenation of higher alkanes.
Ionic reactions of substitution and elimination. Formation of carbocations. Stability and structure. Nucleophilic substitution reactions. SN2 reaction. SN1 reaction. Mechanisms and trends stereochimici.Effetti solvent and leaving group. Elimination reactions. E1 reaction. E2 reaction. Competition between substitution and elimination. Substitution reactions and elimination of biological interest.
Reactions of the C = C double bond. Addition reaction. Addition of hydrogen halides. Markovnikov rule.
(reference books)
-Chimica Organica Essenziale 2a Edizione a cura di Bruno Botta (ediermes) -Guida Ragionata allo Svolgimento di Esercizi si Chimica Organica. D'Auria, Scafati, Zampella (Loghia)
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