Teacher
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CEOLONI Carla
(syllabus)
- Introduction to Genetics. - The genetic material: chemical composition and structure of nucleic acids. Chromatin and chromosomes; structure of eukaryotic chromosome. - DNA replication. - From DNA to proteins: transcription; genetic code; translation and protein synthesis. - Control of gene expression in prokaryotes and eukaryotes. - Brief outline of genomics: size, types of sequences and organization of eukaryotic genomes (examples of sequenced animal and plant genomes, as compared to prokaryotic genomes). Chromosomes and chromatin; structure of the eukaryotic chromosome, karyotypes; chromatin organization: nucleosomes and super-coiling and effect on transcription; eu- and heterochromatin, banding. - Cell cycle, mitosis and meiosis. - Genetics and inheritance of simple traits: Mendel's laws - dominance and recessiveness, segregation in monohybrids and dihybrids, independent assortment, testcross, incomplete dominance, multiple alleles and codominance. Chromosome theory of inheritance. - Linkage and recombination; genetic maps. - Mutations: point mutations; chromosome rearrangements, transposable elements, genomic variations: polyploidy, aploidy, aneuploidy. - Brief outline of genetics of quantitative traits: continuous variation, mean and variance. Experiments by Nilsson-Ehle and Emerson-East. Heritability estimates, response to selection.
(reference books)
Main textbook: - Russell PJ .: Genetics - A molecular approach, Pearson publisher (or similar textbooks, preferably by the same author)
Teaching material of all the topics covered, including any insights, provided by the teacher and available on the teaching materials website
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